nav emailalert searchbtn searchbox tablepage yinyongbenwen piczone journalimg journalInfo journalinfonormal searchdiv searchzone qikanlogo popupnotification paper paperNew
2006, 03, 370-376
西松烷二萜类海洋活性成分研究进展
基金项目(Foundation): 国家海洋高技术研究发展计划项目(2001AA620403,2002AA217081)资助
邮箱(Email):
DOI: 10.16441/j.cnki.hdxb.2006.03.006
发布时间: 2006-05-30
出版时间: 2006-05-30
移动端阅读
摘要:

综述了近年来海洋天然产物,127个西松烷二萜类化合物的分离、结构鉴定以及其生物活性研究进展,为海洋生物的合理开发利用提供科学依据。

Abstract:

This paper reviews the isolation, structure identification and bioactivitiy research of ocean natural products, 127 cembranoid diterpenes, in the past decades, providing scientific evidence for reasonable exploitation and application of oceanic organisms.

参考文献

[1] Dauben W G,Thiessen WE,Resnick P R.Cembrene,a14-mem-bered ring ditepene hydrocarbon[J].J Am Chem Soc,1962,84:2015-2016.

[2] Kobayashi H,Akiyoshi S.Thunbergene,a macrocyclic diterpene[J].Bull ChemSoc Japan,1962,35:1044-1045.

[3] Roberts D L,Rowland R L.Macrocyclicditerpenes,αandβ-4,8,13-duvatriene-1,3-diolsfromtobacco[J].J Org Chem,1962,27:3989-3995.

[4] 林翠悟,苏镜娱.Sinularia属短指软珊瑚化学成分及生理活性的研究概况[J].热带海洋学报,2001,20(4):87-94.

[5] 黄建设,龙丽娟,张恩.海洋天然产物及生理活性研究进展[J].海洋通报,2001,20(4):83-91.

[6] 欧阳高亮,李祺福,田长海.海洋生物抗肿瘤活性物质及其作用机理研究进展[J].海洋科学,2003,27(7):21-24.

[7] 郑其煌,曾陇梅.西松烷型二萜研究进展[J].化学通报,1990,9:9-18.

[8] Chang-Yih Duh,Rei-Shen Hou.Cytotoxic Cembranoidsfromthe Soft CoralsSinularia gibberosaandSarcophyton trocheliophorum[J].J Nat Prod,1996,59:595-598.

[9] Rodriguez A D,Acosta A L.Newcembranoid diterpenes and a ger-anylgeraniol derivative fromthe common Caribbean Sea whipEunicea succinea[J].J Nat Prod,1997,60:1134-1138.

[10] Duh C Y,Wang S K,Weng Y L,et al.Cytotoxic Terpenoids from the Formosan Soft CoralNephthea brassica[J].J Nat Prod,1999,62:1518-1521.

[11] Iwagawa T,Nakashi ma R,Takayama K,et al.New cembranes fromthe soft coralSarcophytonspecies[J].J Nat Prod,1999,62:1046-1049.

[12] Matth啨e G F,K ning G M,Wright A D.Three New Diterpenes fromthe Marine Soft CoralLobophytumcrassum[J].J Nat Prod,1998,61:237-240.

[13] Marville K I,McLean S,Reynolds W F,et al.New cembrane diterpenes of the marine octocoralEunicea tournifortifrom the Eastern Caribbean[J].J Nat Prod,2003,66:1284-1287.

[14] Reyes F,Ard偄A,Mart姫n R,et al.Newcytotoxic cembranes from the Sea PenGyrophyllum sibogae[J].J Nat Prod,2004,67:1190-1192.

[15] Gross H,Wright A D,Beil W,et al.Two new bicyclic cembrano-lides froma newSarcophytonspecies and determination of the abso-lute configurution of sarcoglaucol-16-one[J].Org Biomo Chem,2004,2:1133-1138.

[16] Duh C Y,Wang S K,Weng Y L.Brassicolene,a novel cytotoxic diterpenoid fromthe formosan soft coralNephthea brassica[J].Te-trahedron Lett,2000,41:1401-1403.

[17] Pham N B,Butler MS,Quinn RJ.Naturally occurring vembranes froman AustralianSarcophytonSpecies[J].J Nat Prod,2002,65:1147-1150.

[18] Duh C Y,Wang S K,Huang B T,et al.Cytotoxic cembrenolide diterpenes fromthe formosan soft coralLobophytumcrassum[J].J Nat Prod,2000,63:884-885.

[19] Rashid M A,Gustafson K R,Boyd MR.HI V-inhibitory cembrane derivatives froma Philippines collection of the soft coralLobophytum Species[J].J Nat Prod,2000,63:531-533.

[20] Duh C Y,Wang S K,Chuang S G,et al.Cytotoxic cembrenolides and steroids fromthe formosan soft coralSarcophyton crassocaule[J].J Nat Prod,2000,63:1634-1637.

[21] Iwashi ma M,Matsumoto Y,Takahashi H,et al.New marine cem-brane-type diterpenoids from the okinawan soft coralClavularia koellikeri[J].J Nat Prod,2000,63:1647-1652.

[22] 苏镜娱,闫素君,曾陇梅.柔软肉芝软珊瑚中的新二萜内酯[J].高等学校化学学报,2001,22:1515-1517.

[23] Duh C Y,El-Gamal A A H,Chu C J,et al.New cytotoxic con-stituents from the formosan soft coralsClavularia viridisand Clavularia violacea[J].J Nat Prod,2002,65:1535-1539.

[24] Iwashi ma M,Matsumoto Y,Takenaka Y,et al.New marine diter-penoidsfromthe okinawan soft coralClavularia koellikeri[J].J Nat Prod,2002,65:1441-1446.

[25] Uchio Y,Eguchi S,Nakayama M,et al.The isolation of two si m-pleγ-lactonic cembranolidesfromthe soft coralSinularia mayi[J].Chemistry Lett,1982,277-278.

[26] Gross H,Kehraus S,Nett M,et al.Newcytotoxic cembrane based diterpenes from the soft coralsSarcophyton cherbonnieriand Nephtheasp.[J].Org Biomol Chem,2003,1:944-949.

[27] Yamada K,Ryu K,Miyamoto T,et al.Bioactive terpenoids from octocorallia.4.three newcembrane-type diterpenoids fromthe soft coralLobophytumschoedei[J].J Nat Prod,1997,60:798-801.

[28] Rodr姫guez A D,Acosta AL.Newcembranolidesfromthe gorgonian Eunicea succinea[J].J Nat Prod,1998,61:40-45.

[29] Shi Y P,Rodr姫guez A D,Barnes C L,et al.Newterpenoid con-stituents fromEunicea pinta[J].J Nat Prod,2002,65:1232-1241.

[30] Rodr姫guez A D,Dhasmana H.Further bioactive cembranolide diter-penes fromthe gorgonianEuniceasuccinea[J].J Nat Prod,1993,56:564-570.

[31] Xu L,Patrick B O,Roberge M,et al.New diterpenoids fromthe octocoralPachyclavularia violaceacollected in Papua New Guinea[J].Tetrahedron,2000,56:9031-9037.

[32] SheuJ H,Wang G H,Sung PJ,et al.Pachyclavulariolides G-Land secopachyclavulariaenone A,seven novel diterpenoids fromthe soft coralPachyclavularia violacea[J].Tetrahedron,2001,57:7639-7648.

[33] Venkareswarlu Y,Sridevi K V,Rao M R.Newfuranocembranoid diterpenes fromthe soft coralSinularia maxi ma[J].J Nat Prod,1999,62:756-758.

[34] Rodr姫guez A D,Shi J G,Huang S D.Highly oxygenated pseu-dopterane and cembranolide diterpenesfromthe caribbeanseafeather Pseudopterogorgia bipinnata[J].J Nat Prod,1999,62:1228-1237.

[35] Longeon A,Bourguet-Kondracki M L,Guyot M.Two new cem-brane diterpenes from a madagascan soft coral of the genusSarco-phyton[J].Tetrahedron Lett,2002,43:5937-5939.

[36] Rodr姫guez A D,Shi YP.New metabolitesfromthe West Indian Sea featherPseudopterogorgia bipinnata[J].J Nat Prod,2000,63:1548-1550.

[37] Rodr姫guez A D,Shi Y P.Verrillin:A highly oxygenated marine diterpene based on the novel verrillane carbon skeleton[J].J OrgChem,2000,65:5839-5842.

[38] Duh C Y,Wang S K,Tseng H K,et al.Novel cytotoxic cembra-noids from the soft coralSinularia flexibilis[J].J Nat Prod,1998,61:844-847.

[39] Anjaneyulu AS R,Sagar KS,Rao G V.Newcembranoidlactones fromthe Indian ocean soft coralSinularia flexibilis[J].J Nat Prod,1997,60:9-12.

[40] Su J,Yang R,Kuang Y,et al.A Newcembranolide fromthe soft coralSinularia capillosa[J].J Nat Prod,2000,63:1543-1545.

[41] Lin C W,Su J Y,Zeng L M.Crystal structure of a newcembrano-lide diterpene[J].Chem Res Chin Univ,2002,18:189-191.

[42] Sheu J H,Ahmed A F,Shiue R T,et al.Scabrolides A-D,four new norditerpenoids isolated from the soft coralSinularia scabra[J].J Nat Prod,2002,65:1904-1908.

[43] Zhang WH,Williams I D,Che C T.Chabrolols A,Band C,three new norditerpenesfromthe soft coralNephtheachabroli[J].Tetra-hedron Lett,2001,42:4681-4685.

[44] Reddy N S,Goud T V,Venkateswarlu Y.Seco-Sethukarailin,a novel diterpenoid fromthe soft coralSinularia dissecta[J].J Nat Prod,2002,65:1059-1060.

[45] Duh Chang-Yih,Wang Shang-Kwei,Tseng Hsien-Kai,et al.A novel biscembranoid fromthe formosan soft coralSinularia flexi-bilis[J].Tetrahedron Lett,1998,39:7121-7122.

[46] Iguchi K,Fukaya T,Takahashi H,et al.Stolonilactone,a novel terpenoid-related compound,Isolated fromthe okinawan soft coral Clavularia koellikeri[J].J Org Chem,2004,69:4351-4355.

[47] Rodr姫guez A D,Shi J G.Isolation,structure elucidation,and syn-thesis of bis-gersolanolide,a novel heptacyclic bis-diterpenoid from the gorgonian octocoralPseudopterogorgiabipinnata[J].Org Lett,1999,1:337-340.

[48] Rodr姫guez A D,Shi J C,Shi YP.Isolation,structural characteriza-tion,and synthesis of a naturally occurring bisfuranopseudopterane ether:biskallolide A.Evidence for a Carbocation Intermediate dur-ingthe Facile Conversion of Kallolide Aand Isokallolide Ainto Vari-ous Solvolysis Products[J].J Org Chem,2000,65:3192-3199.

[49] Slattery M,Kamel H N,Fronczek F R,et al.A novel metabolite fromthe hybrid soft coralSinularai maxi ma×Sinularia poly-dactyla:a biosynthetically mixed skeleton linking cembrane and Africanane Terpenoids[J].Tetrahedron Lett,2004,45:1995-1997.

[50] Cobar O M,Rodr姫guez A D,Padilla O L,et al.The calyculagly-cosides:Dilophol-type diterpene glycosides exhibiting antiinflamma-tory activity fromthe caribbean gorgonianEuniceasp.[J].J Org Chem,1997,62:7183-7188.

[51] El Sayed K A,Hamann M T,Waddling C A,et al.Structurally novel bioconversion products of the marine natural product sarcophine effectivelyinhibit JB6cell transformation[J].J Org Chem,1998,63:7449-7455.

[52] Rodr姫guez AD,Shi J G.The first cembrane-pseudopterane cycloiso-merization[J].J Org Chem,1998,63:420-421.

[53] Li W D Z,Li Y,Li Y.Concise and efficient total syntheses of(±)-Sarcophytols Aand B,two antitumor cembrane diterpenoids,by anIntramolecular Mc Murry olefinationstrategy[J].Tetrahedron Lett,1999,40:965-968.

[54] Yue X,Lan J,Li J,et al.An efficient total synthesis of(±)-sinu-lariol-B[J].Tetrahedron,1999,55:133-140.

[55] Lan J,Lui Z,Cen W,et al.The first total synthesis of preverecyn-armin[J].Tetrahedron Lett,1999,40:1963-1966.

[56] Lan J,Liu Z,Yuan H,et al.First total synthesis and absolute con-figuration of marine cembrane diterpenoid(±)-11,12-epoxysar-cophytol A[J].Tetrahedron Lett,2000,41:2181-2184.

基本信息:

DOI:10.16441/j.cnki.hdxb.2006.03.006

中图分类号:O629.61

引用信息:

[1]李国强,张艳玲,林文翰.西松烷二萜类海洋活性成分研究进展[J].中国海洋大学学报(自然科学版),2006(03):370-376.DOI:10.16441/j.cnki.hdxb.2006.03.006.

基金信息:

国家海洋高技术研究发展计划项目(2001AA620403,2002AA217081)资助

发布时间:

2006-05-30

出版时间:

2006-05-30

检 索 高级检索

引用

GB/T 7714-2015 格式引文
MLA格式引文
APA格式引文