杨翔昊,郭威,孙翠竹,李媛媛,徐功娣,李锋民

• 1:中国海洋大学海洋环境与生态教育部重点实验室

摘要(Abstract)：

四环素类抗生素(Tetracyclines, TCs)在生产中的滥用会导致其在环境中的残留，极大提高了人体感染疾病的风险，并且目前仍缺乏快速、有效的检测手段。基于TCs在水中易与Fe~(2+)、Fe~(3+)产生强烈络合的特性，本文制备了一种部分碳化NH_2-MIL-101(Fe)用于水中TCs快速检测的比色检测方法。经惰性气氛煅烧法对NH_2-MIL-101(Fe)进行改性，制备了两种改性材料，并对两种改性材料和前体的表面形貌及化学结构进行了表征。对比了NH_2-MIL-101(Fe)和350、450℃下煅烧的改性材料与土霉素间的络合效果，实验结果表明，3种材料均可与土霉素络合，350℃煅烧得到的部分碳化材料具有最佳催化效果，并显示出良好的稳定性和分散性。在优化的检测条件下(催化剂投加量12μg·mL~(-1)、H_2O_2浓度6 mmol·L~(-1)、TMB浓度5 mmol·L~(-1)、pH=5.5、反应时间40 min),oxTMB在652 nm处的吸光度值与土霉素浓度之间呈现线性关系，线性范围为0.08～50μmol·L~(-1)(R~2=0.982 2)。本文设计的比色方法可实现实际水体中TCs含量的灵敏、特异性检测，为完善水体安全监管体系提供了一定的理论与技术支撑。

关键词(KeyWords)： NH_2-MIL-101(Fe);部分碳化材料;四环素类抗生素;水环境;比色检测方法

Abstract:

Keywords:

基金项目(Foundation): 国家重点研究发展计划项目(2018YFC0406304);; 山东省重大科技创新工程项目(2019JZZY020302)资助~~

作者(Author): 杨翔昊,郭威,孙翠竹,李媛媛,徐功娣,李锋民

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