热休克蛋白22结构和功能研究进展Research Progress in the Structure and Function of Heat Shock Protein 22
杨官品,张蕾,董超华
摘要(Abstract):
热休克蛋白22(HSP22)是唯一在体外能以单体形式存在的小分子热休克蛋白(sHSP),具有分子伴侣功能和激酶活性。HSP22高水平表达促进细胞凋亡而低水平表达抑制凋亡。除此之外,HSP22还在延长寿命、耐热和抗氧化等方面发挥作用。由于其独特的生物学功能,HSP22正成为当今研究热门对象之一。近年来,HSP22在医学方面的研究已取得显著进展,其在海洋生物学方面的研究价值也逐渐得到重视。本文综述了近年来HSP22结构和功能及其在医学和海洋生物学上的研究进展。
关键词(KeyWords): 热休克蛋白22;小热休克蛋白;医学;海洋生物
基金项目(Foundation):
作者(Author): 杨官品,张蕾,董超华
DOI: 10.16441/j.cnki.hdxb.2009.05.027
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